Leeds BRC is based at Chapel Allerton Hospital where the majority of musculoskeletal outpatient appointments for Leeds Teaching Hospitals NHS Trust (LTHT) take place. Rheumatology outpatients sees more than 30,000 patients each year and houses the largest biologics clinic in Europe. There are combined clinics in Dermatology, Respiratory, Renal, Immunology and Gastroenterology, Dermo-rheumatology, and Immuno-rheumatology. The Chapel Allerton Orthopaedic Centre (CHOC) is the LTHT dedicated centre for the diagnosis, management and treatment of adult elective orthopaedic surgery. More than 1400 joint replacements are conducted at CHOC each year.
The BRC is located on the first floor of Chapel Allerton Hospital. Facilities include state of the art research dedicated imaging (MRI and ultrasound) and meeting and conference rooms for up to 50 delegates, including a live link up to operating theatres enabling interactive viewing of joint replacement surgery. In addition there is a state of the art gait and motion analysis laboratory located in the outpatients department. This complements the world class facilities for preclinical testing of joint replacements available at iMBE.
Biosample facilities are also adjacent to the outpatient area in Chapel Allerton Hospital, with biomarker validation supported by laboratory facilities hosted within the Wellcome Trust Brenner Building at St James’s Hospital. Diagnostic and biomarker research is supported by the Leeds NIHR Diagnostic Evidence Cooperative (DEC).
Early phase clinical trials are supported by the Leeds Institute of Clinical Trials Research (LICTR) and the NIHR Clinical Research Facility which has early phase experimental facilities to support musculoskeletal research. Key infrastructure underpinning our translational research includes a mature, rapid referral access from our Yorkshire population of 5 million, which has enabled us to develop well-defined patient cohorts from which targeted treatments can be developed.