Our centre of imaging excellence within the BRC houses state of the art : Magnetic Resonance Imaging (MRI) and ultrasound equipment which allows the application of novel imaging tissue characterisation techniques in musculoskeletal tissues and diseases. Equipment includes:
The imaging unit is led by rheumatologist Professor Philip Conaghan, radiologist Dr Phil O’Connor (MRI) and rheumatologist Dr Richard Wakefield (ultrasound). They are supported by a multidisciplinary research team including radiographers, ultrasonographers, medical physicists and bioengineers, with academic support and guidance provided by LIRMM and iMBE.
The imaging team focus on development of novel imaging techniques and biomarkers, and application of these to support clinical studies, which includes development of imaging protocols, measurement of imaging endpoints and image analysis. They have extensive experience in protocol development and validation of imaging biomarkers. For example, the unit has helped develop current gold standard imaging outcome measures in rheumatoid arthritis (RAMRIS), psoriatic arthritis, spondyloarthropathy and osteoarthritis. High-level post processing expertise and facilities are built into the unit, with analysis solutions available for Windows or Mac using OsiriX, Matlab and Analyse software.
The BRC has an established research collaboration with industry partners, Siemens Healthcare, which is vital to our research capability. This partnership enables early access to pre-product MR software for evaluation within musculoskeletal diseases. For example the Siemens WARP technique reduces the metal distortion artefact seen on MRI scans which is caused by joint replacements by using slice encoding metal artefact correction (SEMAC) and view angle tilting. This novel approach to MR imaging allows us to see if there are complications as a result of the surgery such as loosening or infection of the joint. The BRC, in collaboration with Leeds Medical Technologies Innovation and Knowledge Centre (IKC), has funded large prospective in vitro and in vivo studies assessing the technical accuracy and diagnostic performance and impact of the new technique.
For advice on developing an imaging protocol, please contact:
Dominic Bertham firstname.lastname@example.org
and John Ridgway email@example.com
Kate Smith firstname.lastname@example.org
For an application form to access the MRI or ultrasound imaging facilities, or advice on the costs of using the facilities, please contact
Michelle Davies email@example.com