Leeds BRC is led by Professor Paul Emery, the most highly cited rheumatologist in Europe and listed among the ‘World’s Most Influential Scientific Minds’ (Reuters). Professor Emery leads the rheumatology clinical research of the BRC and is Director of Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), a European Centre of Excellence (top rated 2015). LIRMM is a broad cross-disciplinary group that includes rheumatology, orthopaedics, rehabilitation, radiology, nurses and allied health professionals, built around a novel infrastructure in which the academic and clinical activities are seamlessly linked. LIRMM academics Professor Maya Buch, Professor Dennis McGonagle, Dr Francesco Del Galdo and Professor Ann Morgan lead BRC workstreams on immunotherapies in rheumatoid arthritis, psoriatic arthritis, scleroderma and drug repurposing/treatment toxicity respectively.
LIRMM academic Professor Philip Conaghan is Deputy Director of the BRC and leads the BRC research theme on improving the treatment of osteoarthritis. Within this he also leads a workstream on non surgical treatments for osteoarthritis. BRC workstreams on acellular scaffolds / regenerative devices and longer lasting joint replacements are led by Professor Eileen Ingham and Professor John Fisher respectively, in partnership with the Institute of Medical and Biological Engineering (iMBE). iMBE is the largest bioengineering unit in the UK and winner of the Queen’s Anniversary Prize (2012). It comprises a multi-disciplinary research group in medical engineering and surgical interventions. Facilities include joint simulation (natural and computational), tissue engineering, bioreactors and organ culture, metrology, surface analysis, materials testing and high performance computing.
The depth and strength of the BRC in musculoskeletal research is demonstrated by the involvement of an additional twelve academics with over 50 biomedical translational research publications (2004-2013), and an equal number of emerging research leaders. This is supplemented by an extensive and successful trainee programme including clinicians, allied health professionals, scientists and engineers.
The academic research of the BRC is supported by an experienced and dedicated core team including specialists in MRI and ultrasound, and effective management, administrative and IT support. The BRC is governed through an Executive, Board and Scientific Advisory Board.
Leeds Teaching Hospitals NHS Trust (LTHT) is the second largest Trust in the UK (16,000 employees, 1.5 million patients each year, annual budget of £1.1bn)
University of Leeds is one of the top ten UK research intensive universities (8th highest research income, 10th placed nationally for research power).