Implant retrieval studies have previously informed the design, materials and manufacture of joint replacement prostheses, which will ultimately benefit future patients in terms of increased implant longevity. In this study, explanted prostheses, periprosthetic tissue, and relevant demographic/clinical data, are collected from patients undergoing revision surgery. The samples are processed and stored for future analysis, from which information about wear damage and resistance, and the composition, size and morphology of wear products can be obtained.
Cartilage is the tissue that lines the ends of your bones and forms a smooth surface allowing pain free joint movement. When cartilage is damaged, a painful condition called osteoarthritis may develop. Unfortunately, damaged cartilage does not appear to repair itself. We are trying to improve the treatment of cartilage defects using a new medical device. The surgeon will use this device to hopefully increase the likelihood of your joint repairing. This device works by increasing the number of cells in your knee responsible for repairing the cartilage.
Magnetic resonance imaging (MRI) scans sometimes show abnormal changes in the muscles and bones of athletes who complain of longstanding groin pain. This study aims to see whether these changes are truly linked to symptoms or can occur normally as part of athletic activities.
Investigating outcome following stabilisation of fresh unilateral unstable pertochanteric hip fracture using two different devices.
In the current economic climate there is increasing pressure to identify cost-saving measures across the NHS. Our recent work suggests that many centres are curtailing primary hip and knee arthroplasty follow-up services to deal with the growing pressure on their services. However, such disinvestment is without evidence-base and raises questions of the consequences to patients. This project will examine the requirements for arthroplasty follow-up and produce evidence and consensus-based recommendations as to how, when and on whom follow-up should be conducted. Work packages 1-3 will be discrete research projects, conducted independently. However, knowledge and information from each will feed into and inform the other work streams with some tasks being conducted in parallel.
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